Seminars in Fetal & Neonatal Medicine
Volume 11, Issue 5 , Pages 296-301 , October 2006

Inflammatory responses in the placenta and umbilical cord

References 

  1. Kraus FT, Redline R, Gersell DJ, Nelson DM, Dicke JM. AFIP atlas of nontumor pathology: placental pathology. Washington, DC: American Registry of Pathology; 2004;
  2. Soper DE, Mayhall CG, Froggatt JW. Characterization and control of intraamniotic infection in an urban teaching hospital. Am J Obstet Gynecol. 1996;175:304–309[discussion 309–310]
  3. Redline R, Wilson-Costello D, Borawski E, Fanaroff A, Hack M. The relationship between placental and other perinatal risk factors for neurologic impairment in very low birth weight children. Pediatr Res. 2000;47:721–726
  4. Pankuch GA, Appelbaum PC, Lorenz RP, Botti JJ, Schachter J, Naeye RL. Placental microbiology and histology and the pathogenesis of chorioamnionitis. Obstet Gynecol. 1984;64:802–806
  5. Zhang JM, Kraus FT, Aquino TI. Chorioamnionitis: a comparative histologic, bacteriologic, and clinical study. Int J Gynecol Pathol. 1985;4:1–10
  6. Hillier SL, Martius J, Krohn M, Kiviat N, Holmes KK, Eschenbach DA. A case–control study of chorioamnionic infection and histologic chorioamnionitis in prematurity. N Engl J Med. 1988;319:972–980
  7. Gibbs RS, Romero R, Hillier SL, Eschenbach DA, Sweet RL. A review of premature birth and subclinical infection. Am J Obstet Gynecol. 1992;166:1515–1528
  8. Gardella C, Riley DE, Hitti J, Agnew K, Krieger JN, Eschenbach D. Identification and sequencing of bacterial rDNAs in culture-negative amniotic fluid from women in premature labor. Am J Perinatol. 2004;21:319–323
  9. Yoon BH, Romero R, Kim CJ, Jun JK, Gomez R, Choi JH, et al. Amniotic fluid interleukin-6: a sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity. Am J Obstet Gynecol. 1995;172(3):960–970
  10. Goetzl L, Evans T, Rivers J, Suresh MS, Lieberman E. Elevated maternal and fetal serum interleukin-6 levels are associated with epidural fever. Am J Obstet Gynecol. 2002;187:834–838
  11. Genc MR, Onderdonk A, Witkin SS. Innate immune system gene polymorphisms in women with vulvovaginal infections. Curr Infect Dis Rep. 2004;6:462–468
  12. Medzhitov R, Janeway CA. Decoding the patterns of self and nonself by the innate immune system. Science. 2002;296:298–300
  13. Steel JH, Malatos S, Kennea N, Edwards AD, Miles L, Duggan P, et al. Bacteria and inflammatory cells in fetal membranes do not always cause preterm labor. Pediatr Res. 2005;57(3):404–411
  14. Burgess AM, Hutchins GM. Inflammation of the lungs, umbilical cord and placenta associated with meconium passage in utero. Review of 123 autopsied cases. Pathol Res Pract. 1996;192:1121–1128
  15. Fraser RB, Wright JR. Eosinophilic/T-cell chorionic vasculitis. Pediatr Dev Pathol. 2002;5:350–355
  16. Khong TY, Bendon RW, Qureshi F, Redline RW, Gould S, Stallmach T, et al. Chronic deciduitis in the placental basal plate: definition and inter-observer reliability. Hum Pathol. 2000;31:292–295
  17. Stanek J, Al-Ahmadie HA. Laminar necrosis of placental membranes: a histologic sign of uteroplacental hypoxia. Pediatr Dev Pathol. 2005;8:34–42
  18. Andrews WW, Hauth JC, Goldenberg RL. Infection and preterm birth. Am J Perinatol. 2000;17:357–365
  19. Ghidini A, Salafia CM. Histologic placental lesions in women with recurrent preterm delivery. Acta Obstet Gynecol Scand. 2005;84:547–550
  20. Hill GB. Preterm birth: associations with genital and possibly oral microflora. Ann Periodontol. 1998;3:222–232
  21. Hill GB. Investigating the source of amniotic fluid isolates of fusobacteria. Clin Infect Dis. 1993;16(Suppl. 4):S423–S424
  22. Han YW, Redline RW, Li M, Yin L, Hill GB, McCormick TS. Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth. Infect Immun. 2004;72:2272–2279
  23. Gibbs RS. Chorioamnionitis and bacterial vaginosis. Am J Obstet Gynecol. 1993;169:460–462
  24. Simhan HN, Caritis SN, Krohn MA, Martinez de Tejada B, Landers DV, Hillier SL. Decreased cervical proinflammatory cytokines permit subsequent upper genital tract infection during pregnancy. Am J Obstet Gynecol. 2003;189:560–567
  25. Dammann O, Allred EN, Genest DR, Kundsin RB, Leviton A. Antenatal mycoplasma infection, the fetal inflammatory response and cerebral white matter damage in very-low-birthweight infants. Paediatr Perinat Epidemiol. 2003;17:49–57
  26. Lyon A. Chronic lung disease of prematurity. The role of intra-uterine infection. Eur J Paediatr. 2000;159:798–802
  27. Blanc W. Amniotic infection syndrome: pathogenesis, morphology, and significance in circumnatal mortality. Clin Obstet Gynecol. 1959;2:705–734
  28. Redline RW, Faye-Petersen O, Heller D, Qureshi F, Savell V, Vogler C. Amniotic infection syndrome: nosology and reproducibility of placental reaction patterns. Pediatr Dev Pathol. 2003;6:435–448
  29. Acute and chronic inflammation. In:  Kumar V,  Abbas AK,  Fausto N editor. Robbins & Cotran's pathologic basis of disease. 7th ed.. Philadelphia, PA: Elsevier Saunders; 2005;p. 56–57
  30. Gravett MG, Witkin SS, Haluska GJ, Edwards JL, Cook MJ, Novy MJ. An experimental model for intraamniotic infection and preterm labor in rhesus monkeys. Am J Obstet Gynecol. 1994;171:1660–1667
  31. Gravett MG, Novy MJ, Rosenfeld RG, Reddy AP, Jacob T, Turner M, et al. Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers. JAMA. 2004;292(4):462–469
  32. Galask RP, Varner MW, Petzold CR, Wilbur SL. Bacterial attachment to the chorioamniotic membranes. Am J Obstet Gynecol. 1984;148:915–928
  33. Ohyama M, Itani Y, Yamanaka M, Goto A, Kato K, Ijiri R, et al. Re-evaluation of chorioamnionitis and funisitis with a special reference to subacute chorioamnionitis. Hum Pathol. 2002;33(2):183–190
  34. Jones SA. Directing transition from innate to acquired immunity: defining a role for IL-6. J Immunol. 2005;175:3463–3468
  35. Kazzi SN, Jacques SM, Qureshi F, Quasney MW, Kim UO, Buhimschi IA. Tumor necrosis factor-alpha allele lymphotoxin-alpha+250 is associated with the presence and severity of placental inflammation among preterm births. Pediatr Res. 2004;56:94–98
  36. Keenan WJ, Steichen JJ, Mahmood K, Altshuler G. Placental pathology compared with clinical outcome. Am J Dis Child. 1977;131:1224–1227
  37. Gomez B, Romero R, Ghezzi F, Yoon BH, Mazor M, Berry SM. The fetal inflammatory response syndrome. Am J Obstet Gynecol. 1998;179:194–202
  38. Leviton A, Paneth N, Reuss ML, Susser M, Allred EN, Dammann O, et al. Maternal infection, fetal inflammatory response, and brain damage in very low birth weight infants. Developmental Epidemiology Network Investigators. Pediatr Res. 1999;46(5):566–575
  39. Craven CM, Ward K. Fetal endothelial cells express vascular cell adhesion molecule in the setting of chorioamnionitis. Am J Reprod Immunol. 2000;43:259–263
  40. Kim CJ, Yoon BH, Romero R, BinMoon J, Kim M, Park SS, et al. Umbilical arteritis and phlebitis mark different stages of the fetal inflammatory response. Am J Obstet Gynecol. 2001;185(2):496–500
  41. Rogers BB, Alexander JM, Head J, McIntire D, Leveno KJ. Umbilical vein interleukin-6 levels correlate with the severity of placental inflammation and gestational age. Hum Pathol. 2002;33:335–340
  42. Bejar R, Wozniak P, Allard M, Benirschke K, Vaucher Y, Coen R, et al. Antenatal origin of neurologic damage in newborn infants. I. Preterm infants. Am J Obstet Gynecol. 1988;159:357–363
  43. Mittendorf R, Montag AG, MacMillan W, Janeczek S, Pryde PG, Besinger RE, et al. Components of the systemic fetal inflammatory response syndrome as predictors of impaired neurologic outcomes in children. Am J Obstet Gynecol. 2003;188(6):1438–44
  44. Kim CJ, Yoon BH, Kim M, Park JO, Cho SY, Chi JG. Histo-topographic distribution of acute inflammation of the human umbilical cord. Pathol Int. 2001;51:861–865
  45. Dammann O, Allred EN, Leviton A, Shen-Schwarz S, Heller D, Genest DR, et al. Fetal vasculitis in preterm newborns: interrelationships, modifiers, and antecedents. Placenta. 2004;25(10):788–796
  46. Steel JH, O'Donoghue K, Kennea NL, Sullivan MH, Edwards AD. Maternal origin of inflammatory leukocytes in preterm fetal membranes, shown by fluorescence in situ hybridisation. Placenta. 2005;26:672–677
  47. Lee SD, Kim MR, Hwang PG, Shim SS, Yoon BH, Kim CJ. Chorionic plate vessels as an origin of amniotic fluid neutrophils. Pathol Int. 2004;54:516–522
  48. Scott RJ, Peat D, Rhodes CA. Investigation of the fetal pulmonary inflammatory reaction in chorioamnionitis, using an in situ Y chromosome marker. Pediatr Pathol. 1994;14:997–1003
  49. Hood IC, DeSa DJ, Whyte RK. The inflammatory response in candidal chorioamnionitis. Hum Pathol. 1983;14:984–990
  50. Navarro C, Blanc WA. Subacute necrotizing funisitis. A variant of cord inflammation with a high rate of perinatal infection. J Pediatr. 1974;85:689–697
  51. Redline RW, Wilson-Costello D, Borawski E, Fanaroff AA, Hack M. Placental lesions associated with neurologic impairment and cerebral palsy in very low birth weight infants. Arch Pathol Lab Med. 1998;122:1091–1098
  52. Redline RW. Severe fetal placental vascular lesions in term infants with neurologic impairment. Am J Obstet Gynecol. 2005;192:452–457
  53. Russell P. Inflammatory lesions of the human placenta. Placenta. 1980;1:227–244
  54. Knox WF, Fox H. Villitis of unknown aetiology: its incidence and significance in placentae from a British population. Placenta. 1984;5:395–402
  55. Redline RW, Patterson P. Villitis of unknown etiology is associated with major infiltration of fetal tissue by maternal inflammatory cells. Am J Pathol. 1993;143:473–479
  56. Labarrere CA, Faulk W. Maternal cells in chorionic villi from placentae of normal and abnormal human pregnancies. Am J Reprod Immunol. 1995;33:54–59
  57. Kapur P, Rakheja D, Gomez AM, Sheffield J, Sanchez P, Rogers BB. Characterization of inflammation in syphilitic villitis and in villitis of unknown etiology. Pediatr Dev Pathol. 2004;7:453–458
  58. Redline RW, Abramowsky CR. Clinical and pathologic aspects of recurrent placental villitis. Hum Pathol. 1985;16:727–731
  59. Redline RW, Ariel I, Baergen RN, et al. Fetal vascular obstructive lesions: nosology and reproducibility of placental reaction patterns. Pediatr Devel Pathol. 2004;7:443–452
  60. Ocejo-Vinyals JG, Lozano MJ, Sanchez-Velasco P, Escribano de Diego J, Paz-Miguel JE, Leyva-Cobian F. An unusual concurrence of graft versus host disease caused by engraftment of maternal lymphocytes with DiGeorge anomaly. Arch Dis Child. 2000;83:165–169
  61. Whitington PF, Malladi P. Neonatal hemochromatosis: is it an alloimmune disease?. J Pediatr Gastroenterol Nutr. 2005;40:544–549
  62. Reed AM, Picornell YJ, Harwood A, Kredich DW. Chimerism in children with juvenile dermatomyositis. Lancet. 2000;356:2156–2157

PII: S1744-165X(06)00022-9

doi: 10.1016/j.siny.2006.02.011

Seminars in Fetal & Neonatal Medicine
Volume 11, Issue 5 , Pages 296-301 , October 2006

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