Seminars in Fetal & Neonatal Medicine
Volume 12, Issue 1 , Pages 71-77, February 2007

Impact of maternal nutrition and metabolism on health of the offspring

  • Liza H. Kunz

      Affiliations

    • University of California – Davis, Department of Obstetrics and Gynecology, 4860 Y Street, Suite 2500, Sacramento, CA 95817, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 916 734 6447; fax: +1 916 734 6047.
  • ,
  • Janet C. King

      Affiliations

    • Children's Hospital Oakland Research Institute, Oakland, California, USA

published online 03 January 2007.

Summary

Since the original publication of the theory of the fetal origins of adult diseases more than 15years ago, extensive epidemiological studies have linked the environment in utero to adult health. Maternal nutrition and metabolism are major mechanisms by which the intrauterine environment programs the health of the offspring. Both growth-restricted and overgrown fetuses are at risk for postnatal disease. This paper summarizes the nutritional and metabolic causes of both these conditions and also reviews the interventions that have been tested to mitigate these effects.

Keywords: Barker hypothesis, Fetal programming, Intrauterine growth restriction, Macrosomia, Maternal nutrition

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S1744-165X(06)00104-1

doi:10.1016/j.siny.2006.10.010

Seminars in Fetal & Neonatal Medicine
Volume 12, Issue 1 , Pages 71-77, February 2007