Seminars in Fetal & Neonatal Medicine
Volume 12, Issue 4 , Pages 250-258, August 2007

Epo and other hematopoietic factors

  • Sandra Juul

      Affiliations

    • Department of Pediatrics, Division of Neonatology, Health Sciences Building, University of Washington, Box 356320, Seattle, WA 98195, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 206 221 6814; fax: +1 206 543 8926.
    • ,
  • Ursula Felderhoff-Mueser

      Affiliations

    • Department of Neonatology, Universitätsmedizin Berlin, Berlin, Germany

published online 26 February 2007.

Summary 

The growth factors erythropoietin and granulocyte-colony stimulating factor have hematopoietic and non-hematopoietic functions. Both are used clinically in their recombinant forms. Both also have interesting tissue-protective effects in other organs, which are unrelated to their hematopoietic functions. They have clinical hematopoietic uses in neonatal populations and in experimental non-hematopoietic research, and clinical potential as neuroprotective or tissue-protective agents.

Keywords: Development, Erythropoietin, G-CSF, Growth factor, Neonatal brain injury, Neurogenesis, Neuroprotection

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PII: S1744-165X(07)00016-9

doi:10.1016/j.siny.2007.01.015

Seminars in Fetal & Neonatal Medicine
Volume 12, Issue 4 , Pages 250-258, August 2007

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