Seminars in Fetal & Neonatal Medicine
Volume 14, Issue 4 , Pages 200-203, August 2009

Bacterial vaginosis: A problematic infection from both a perinatal and neonatal perspective

  • Jeff M. Denney

      Affiliations

    • Department of Obstetrics & Gynecology, Division of Maternal–Fetal Medicine, University of Utah, Salt Lake City, UT, USA
  • ,
  • Jennifer F. Culhane

      Affiliations

    • Department of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA
    • Corresponding Author InformationCorresponding author. Address: NCS CHOP Study Center, 34th & Civic, CHOP North – Suite 880, Philadelphia, PA 19104-4399, USA. Tel.: +1 267 426 6844; fax: +1 267 426 5615.

published online 13 April 2009.

Summary 

Bacterial vaginosis (BV) infections are common in women of reproductive age and are easily diagnosed and treatable. Aside from being an annoyance when symptoms of discharge, odor, and pruritus occur in the gravid female, BV infections increase risk of late miscarriage, preterm labor, preterm premature rupture of membranes, and, consequently, preterm delivery. Antepartum and puerperal issues such as chorioamnionitis and endometritis are increased in the context of maternal BV. Moreover, the morbidities and mortality of preterm delivery are consequently increased as a result of BV during pregnancy. Although the pathology associated with BV appears to result from inflammation, more investigation is needed in terms of designing guidelines for appropriate screening and treatment for the prevention of adverse outcomes.

Keywords: Bacterial vaginosis, Morbitity, Mortality, Pregnancy

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PII: S1744-165X(09)00009-2

doi:10.1016/j.siny.2009.01.008

Seminars in Fetal & Neonatal Medicine
Volume 14, Issue 4 , Pages 200-203, August 2009