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Pulmonary hypertension in the newborn – Towards precision medicine

Published:August 10, 2022DOI:https://doi.org/10.1016/j.siny.2022.101382
      Pulmonary hypertension (PHT) is a common cardio-pulmonary emergency in the neonatal patient. It is a disorder of transitional circulation with persistence of fetal circulatory patterns and ventilation-perfusion mismatch. Infants with pulmonary hypertension require timely assessment and management to improve short- and long-term outcomes. There have been significant advances in the understanding of the pathophysiology over the past decade but the classification of PHT in newborn infants and approaches to management are still evolving.
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