Neonatal ECMO survivors: the late emergence of hidden morbidities – an unmet need for long-term follow-up

  • Aparna Hoskote
    Corresponding author. Consultant in Cardiac Intensive Care Honorary Associate Professor, UCL Institute of Cardiovascular Science Great Ormond Street Hospital for Children NHS Foundation Trust London WC1N 3JH, UK Tel.: +44 2074059200; fax: +44 2078138262
    Cardiac Intensive Care Unit, Heart and Lung Directorate, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK
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  • Maayke Hunfeld
    Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children’s Hospital, University Medical Center Rotterdam, the Netherlands
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  • Maura O’Callaghan
    Cardiac Intensive Care Unit, Heart and Lung Directorate, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK
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  • Hanneke IJsselstijn
    Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children’s Hospital, University Medical Center Rotterdam, the Netherlands
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Published:November 24, 2022DOI:
      Since the initiation of Extracorporeal Life Support Organization (ELSO) Registry in 1989, more than 47,000 neonates treated with extracorporeal membrane oxygenation (ECMO) have been registered worldwide with an overall survival rate of 65% to transfer or hospital discharge.


      A brief overview of the last 5-year ELSO Registry data reveals an important shift in the indication for neonatal ECMO (Figure 1A and 1B) with a notable increase in neonatal cardiac ECMO (44% to 52%, respectively).


      Figure 1
      Figure 1Change in indication for neonatal ECMO treatment over the years


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